Content (Syllabus outline)
Introduction to industrial bioprocesses and application of modern biotechnology approaches for development of industrial biocultures and bioprocesses. Application of omics/ systems biology approaches in analysis and development of industrial processes. Development and application of classical methods of mutagenesis and selection as well as modern methods of directed evolution in the selection and strain improvement processes. Application of microfluidics in strain selection. Use of modern methods of recombinant DNA in strain and process development such as CRISP-Cas, TAR cloning and recombineering. Comparison of classical and novel approaches in strain development, and comparative analysis of these approaches. Introduction to novel concepts of model heterologous hosts, so called »microbial chassis« or »cell factories«, and their use in industrial process development. Advantages and potential disadvantages of microbial chassis. Tools, methods and optimised bioprocesses, which are used for production of bioproducts from heterologous sources. Presentation of Industrial cases. Intellectual property management in relation to industrial microorganisms, bioprocesses and new bioproducts development. Preparation and analysis of patent/patent applications in the area of industrial biotechnology.
Prerequisites
Requirements for enrolment:
Completed exams in Mathematics, Statistics, Chemistry, Biochemistry, Genetics or Microbial genetics, Molecular biology, Physiology or Microbial physiology
Terms of Prerequisites:
Written examination:
- attending practicals
Exam:
- attending lectures
- passed written examination
- completed seminar
- completed field work